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  • RNA-primed DNA synthesis in vitro..
  • RNA-primed DNA synthesis in vitro..
  • African Masculinities: Men in Africa from the Late 19th Century to the Present?
  • Principles of Biochemistry/Cell Metabolism I: DNA replication.

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Original Research ARTICLE

This is a preview of subscription content, log in to check access. Davies PA, Gray G. Long-range PCR. Methods Mol Biol — PubMed Google Scholar.

Principles of Biochemistry/Cell Metabolism I: DNA replication

Goren A, Cedar H. Replicating by the clock.

Nat Rev Mol Cell Biol — Long PCR based amplification of the entire mitochondrial genome from single parasitic nematodes. Mol Cell Probes — Kelman Z.

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DNA replication in the third domain of life. Curr Protein Pept Sci — Initiation of eukaryotic DNA replication: regulation and mechanisms. If you would like to redeem your KAB credit, please log in. Subcription rates.

The chemicals 9,dimethylbenzanthracene DMBA , ethionine, daunorubicin, actinomycin D, l- 2-chloroethyl-1 -nitrosourea CCNU , steroids, croton oil and dimethylsulfoxide DMSO were used in order to correlate their effect on the in vitro synthesis of normal and cancer DNA, on DNA strand separation and on accelerated in vivo multiplication of cancer cells. Under the same conditions, the synthesis of DNA originating from healthy tissues is only slightly enhanced, except in the case of croton oil and DMSO.

These substances are almost equally active on cancer and normal DNA. Although both cancer and normal DNA contain a large amount of double-stranded regions, the extent of DNA strand separation measured by the increase in UV absorbance hyperchromicity in the presence of each compound tested is much higher for all cancer DNA than for corresponding normal DNA.

SV40 DNA Replication In Vitro | SpringerLink

Additive and differential effects of various compounds on cancer DNA strand separation can be observed. There is thus a possible correlation between DNA strand separation, DNA synthesis, multiplication and differentiation of cancer cells in the presence of the above compunds, which is different from the response of normal cells to these compounds. Forgot your password?

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